Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | SLC7A11 | Q9UPY5 | 1/20 | 0.39 |
| ▸ | CPB2 | Q96IY4 | 3/20 | 0.36 |
| ▸ | ENPEP | Q07075 | 6/20 | 0.35 |
| ▸ | GLRA1 | P23415 | 1/20 | 0.32 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.32 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.32 |
| ▸ | CPN1 | P15169 | 1/20 | 0.32 |
| ▸ | ANPEP | P15144 | 2/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349420 | 1.00 | PTGS1 (0.39) | PTGS1SLC7A11CPB2ENPEPGLRA1 | |
| SCHEMBL27656950 | 0.94 | PTGS1 (0.35) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL1493217 | 0.94 | PTGS1 (0.35) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL27677168 | 0.88 | PTGS1 (0.34) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL27677171 | 0.88 | PTGS1 (0.34) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL1493232 | 0.85 | PTGS1 (0.45) | PTGS1SLC7A11CPB2ENPEP | |
| SCHEMBL4082389 | 0.80 | OR51E2 (0.33) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL15756799 | 0.80 | OR51E2 (0.33) | GLRA1SLC6A9OR51E2 | |
| SCHEMBL9802393 | 0.78 | PTGS1 (0.34) | PTGS1SLC7A11ENPEPFOLH1 | |
| SCHEMBL9802385 | 0.78 | PTGS1 (0.34) | PTGS1SLC7A11ENPEPFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750610-B1 | PIPERIDYL-4-SUBSTITUTED THYROSINE DERIVATIVES AS SCINTIGRAPHIC IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOSIS | DIATIDE INC (US) | 2001-12-12 | — | — | EP | disclosed |
| US-6248304-B1 | PIPERIDINE COMPOUND | BERLEX LABORATORIES, INC. | 2001-06-19 | — | — | US | disclosed |
| EP-0750610-A1 | PIPERIDYL-4-SUBSTITUTED THYROSINE DERIVATIVES AS SCINTIGRAPHIC IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOSIS | Diatide, Inc. (US) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995025720-A1 | PIPERIDYL-4-SUBSTITUTED THYROSINE DERIVATIVES AS SCINTIGRAPHIC IMAGING AGENTS FOR THE DIAGNOSIS OF THROMBOSIS | DIATECH, INC. (US) | 1995-09-28 | — | — | WO | disclosed |