Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 6/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.35 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.35 |
| ▸ | HSD17B3 | P37058 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.32 |
| ▸ | TDP2 | O95551 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.31 |
| ▸ | RAB9A | P51151 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | THRB | P10828 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16389372 | 0.90 | BACE1 (0.33) | PDK2TYRO3NTRK2CLK4DYRK1B | |
| SCHEMBL23805442 | 0.89 | HSD17B3 (0.33) | PDK2TYRO3NTRK2CLK4DYRK1B | |
| SCHEMBL16389437 | 0.89 | HSD17B3 (0.33) | PDK2TYRO3NTRK2CLK4DYRK1B | |
| SCHEMBL16389457 | 0.86 | NPC1 (0.37) | PDK2HSD17B3DRD2MCHR1NPC1 | |
| SCHEMBL14933439 | 0.85 | TYRO3 (0.36) | PDK2TYRO3NTRK2CLK4DYRK1B | |
| SCHEMBL16389438 | 0.84 | HSD17B3 (0.32) | TYRO3NTRK2CLK4DYRK1BHSD17B3 | |
| SCHEMBL16389468 | 0.83 | HSD17B3 (0.30) | HSD17B3 | |
| SCHEMBL14933510 | 0.82 | — | — | |
| SCHEMBL18326500 | 0.81 | HSD17B3 (0.34) | PDK2HSD17B3TDP2NPC1RAB9A | |
| SCHEMBL16389453 | 0.79 | HSD17B3 (0.36) | PDK2TYRO3NTRK2CLK4DYRK1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| EP-2773721-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2013064206-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |