SCHEMBL14933439

SCHEMBL14933439

CC1(C)c2cc(-c3ccccc3)ccc2N2Cc3ccccc3-c3cc(-c4ccccc4)cc1c32

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYRO3 Q06418 1/20 0.36
NTRK2 Q16620 1/20 0.36
CLK4 Q9HAZ1 1/20 0.36
DYRK1B Q9Y463 1/20 0.36
HSD17B3 P37058 2/20 0.36
KMT2A Q03164 2/20 0.33
TSHR P16473 1/20 0.33
LMNA P02545 4/20 0.33
NPC1 O15118 3/20 0.33
RAB9A P51151 3/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
TDP2 O95551 1/20 0.33
MCHR1 Q99705 1/20 0.32
SRD5A1 P18405 1/20 0.32
CTSD P07339 1/20 0.32
ALDH1A1 P00352 2/20 0.32
MAPT P10636 2/20 0.32
THRB P10828 2/20 0.32
PDK2 Q15119 1/20 0.32
KDM4E B2RXH2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933404 0.85 PDK2 (0.36) TYRO3NTRK2CLK4DYRK1BHSD17B3
SCHEMBL16389453 0.81 HSD17B3 (0.36) TYRO3NTRK2CLK4DYRK1BHSD17B3
SCHEMBL16389372 0.81 BACE1 (0.33) TYRO3NTRK2CLK4DYRK1BHSD17B3
SCHEMBL16389437 0.80 HSD17B3 (0.33) TYRO3NTRK2CLK4DYRK1BHSD17B3
SCHEMBL23805442 0.80 HSD17B3 (0.33) TYRO3NTRK2CLK4DYRK1BHSD17B3
SCHEMBL20152305 0.77 MEN1 (0.36) KMT2ALMNANPC1RAB9ASMN1; SMN2
SCHEMBL16389468 0.77 HSD17B3 (0.30) HSD17B3
SCHEMBL15937275 0.75 PGR (0.33) HSD17B3KMT2ATDP2SRD5A1CTSD
SCHEMBL15937316 0.75 PGR (0.33) HSD17B3KMT2ATDP2SRD5A1CTSD
SCHEMBL15937360 0.75 PGR (0.33) HSD17B3KMT2ATDP2SRD5A1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
US-20150340621-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-26 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2014094964-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-06-26 WO disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed