SCHEMBL14933438

SCHEMBL14933438

O=c1c2cccc3ncc4cccc(c4c32)n1-c1cc(-c2ccccc2)cc(-c2ccccc2)c1

nearest known ligand 0.41

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 5/20 0.41
MEN1 O00255 4/20 0.41
GAA P10253 2/20 0.41
MAPT P10636 4/20 0.40
HSP90AA1 P07900 1/20 0.40
PDE10A Q9Y233 1/20 0.40
MET P08581 1/20 0.37
HSD17B10 Q99714 2/20 0.37
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 2/20 0.36
NPY1R P25929 1/20 0.36
NPY2R P49146 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
TSHR P16473 1/20 0.36
BRCA1 P38398 1/20 0.36
RXFP1 Q9HBX9 1/20 0.35
ADORA3 P0DMS8 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14933515 0.82 KMT2A (0.48) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL14933410 0.81 KMT2A (0.47) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL14933413 0.77 KMT2A (0.50) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL14933618 0.77 KMT2A (0.43) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL14933435 0.77 KMT2A (0.50) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL14933402 0.77 KMT2A (0.40) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL15999687 0.76 POLB (0.34) KMT2AMEN1GAAMAPTPDE10A
SCHEMBL14933436 0.75 POLB (0.35) KMT2AMEN1GAAMAPTPDE10A
SCHEMBL14933425 0.74 KMT2A (0.41) KMT2AMEN1GAAMAPTHSP90AA1
SCHEMBL14933341 0.72 KMT2A (0.53) KMT2AMEN1MAPTHSP90AA1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
US-9337430-B2 Organic electroluminescent device MERCK PATENT GMBH (DE) 2016-05-10 US disclosed
EP-2773721-B1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2015-11-25 EP disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
US-20140249308-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2014-09-04 US disclosed
WO-2013064206-A1 ORGANIC ELECTROLUMINESCENT DEVICE MERCK PATENT GMBH (DE) 2013-05-10 WO disclosed