Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 8/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | TNKS | O95271 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GPR3 | P46089 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.48 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15338391 | 0.87 | PARP1 (1.00) | PARP1KDM4EAURKAMEN1TNKS | |
| SCHEMBL12750384 | 0.87 | PARP1 (1.00) | PARP1KDM4EAURKAMEN1TNKS | |
| SCHEMBL30910462 | 0.87 | PARP1 (1.00) | PARP1KDM4EAURKAMEN1TNKS | |
| SCHEMBL5879545 | 0.84 | PARP1 (0.81) | PARP1KDM4EAURKAMEN1TNKS | |
| SCHEMBL30322789 | 0.79 | PARP1 (0.55) | PARP1KDM4ELMNAPMP22GABRA1 | |
| SCHEMBL12396542 | 0.79 | PARP1 (0.55) | PARP1KDM4ELMNAPMP22GABRA1 | |
| SCHEMBL21052453 | 0.77 | PARP1 (0.71) | PARP1KDM4EMEN1TNKSALDH1A1 | |
| SCHEMBL30231234 | 0.77 | PARP1 (0.71) | PARP1KDM4EMEN1TNKSALDH1A1 | |
| SCHEMBL17536725 | 0.76 | PARP1 (0.59) | PARP1KDM4EAURKAGABRA1GABRG2 | |
| SCHEMBL2442863 | 0.76 | PARP1 (0.69) | PARP1KDM4EAURKAMEN1TNKS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| US-9337430-B2 | Organic electroluminescent device | MERCK PATENT GMBH (DE) | 2016-05-10 | — | — | US | disclosed |
| EP-2773721-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2015-11-25 | — | — | EP | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| US-20140249308-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2014-09-04 | — | — | US | disclosed |
| WO-2013064206-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | MERCK PATENT GMBH (DE) | 2013-05-10 | — | — | WO | disclosed |