Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 12/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.52 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.48 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.45 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6037887 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL6037889 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10326494 | 0.87 | KDM4E (0.58) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10327190 | 0.84 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17676996 | 0.84 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10326670 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10327014 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL17676997 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL10326975 | 0.84 | ALDH1A1 (0.49) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL25309402 | 0.82 | GAA (0.56) | GAACXCR4HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013066838-A1 | COMPOUNDS AND METHODS | GLAXOSMITHKLINE LLC (US) | 2013-05-10 | — | — | WO | disclosed |