Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 13/20 | 0.79 |
| ▸ | CCR5 | P51681 | 2/20 | 0.61 |
| ▸ | USP2 | O75604 | 5/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934390 | 0.88 | EPHX2 (1.00) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934403 | 0.87 | EPHX2 (0.74) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934571 | 0.86 | EPHX2 (0.64) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL15171035 | 0.85 | EPHX2 (0.92) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934478 | 0.84 | EPHX2 (0.92) | EPHX2USP2CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL14934580 | 0.84 | EPHX2 (0.86) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934417 | 0.82 | EPHX2 (0.68) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934437 | 0.82 | EPHX2 (0.67) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934365 | 0.82 | EPHX2 (0.59) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934360 | 0.82 | EPHX2 (0.67) | EPHX2USP2CYP3A4TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |