Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 11/20 | 0.74 |
| ▸ | USP2 | O75604 | 8/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934371 | 0.89 | EPHX2 (0.64) | EPHX2USP2CYP3A4TSHRCYP2C9 | |
| SCHEMBL14934398 | 0.87 | EPHX2 (0.79) | EPHX2USP2CYP3A4TSHRCYP2C9 | |
| SCHEMBL14934390 | 0.85 | EPHX2 (1.00) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934482 | 0.85 | EPHX2 (0.59) | EPHX2USP2CYP3A4TSHRCYP2C9 | |
| SCHEMBL14934414 | 0.83 | CYP3A4 (0.70) | EPHX2USP2CYP3A4TSHRCYP2C9 | |
| SCHEMBL14934357 | 0.83 | CYP3A4 (0.66) | EPHX2USP2CYP3A4TSHRCYP2C9 | |
| SCHEMBL15171035 | 0.82 | EPHX2 (0.92) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934428 | 0.82 | EPHX2 (0.66) | EPHX2USP2CYP3A4TSHRCYP2C9 | |
| SCHEMBL14934478 | 0.81 | EPHX2 (0.92) | EPHX2USP2CYP3A4CYP2C9CYP1A2 | |
| SCHEMBL14934422 | 0.81 | EPHX2 (0.55) | EPHX2USP2CYP3A4TSHRCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |