Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.76 |
| ▸ | USP2 | O75604 | 6/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934509 | 0.91 | EPHX2 (0.63) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934356 | 0.90 | EPHX2 (0.76) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934496 | 0.87 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934567 | 0.85 | EPHX2 (0.78) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934581 | 0.82 | EPHX2 (0.57) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934531 | 0.82 | EPHX2 (0.57) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934570 | 0.82 | EPHX2 (0.76) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934437 | 0.80 | EPHX2 (0.67) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934369 | 0.80 | EPHX2 (0.76) | EPHX2USP2CYP3A4TSHRCYP1A2 | |
| SCHEMBL14934362 | 0.79 | EPHX2 (0.76) | EPHX2USP2CYP3A4TSHRCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |