Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 14/20 | 0.78 |
| ▸ | NAMPT | P43490 | 3/20 | 0.52 |
| ▸ | CNR2 | P34972 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14934515 | 0.87 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934356 | 0.85 | EPHX2 (0.76) | EPHX2CNR2USP2CYP2C9CYP1A2 | |
| SCHEMBL14934436 | 0.85 | EPHX2 (0.76) | EPHX2USP2CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL14934509 | 0.84 | EPHX2 (0.63) | EPHX2CNR2USP2CYP2C9CYP1A2 | |
| SCHEMBL14934581 | 0.82 | EPHX2 (0.57) | EPHX2NAMPTUSP2CYP1A2CYP3A4 | |
| SCHEMBL14934514 | 0.81 | EPHX2 (1.00) | EPHX2 | |
| SCHEMBL14934531 | 0.80 | EPHX2 (0.57) | EPHX2NAMPTUSP2CYP2C9CYP1A2 | |
| SCHEMBL14934570 | 0.79 | EPHX2 (0.76) | EPHX2USP2CYP2C9CYP1A2CYP3A4 | |
| SCHEMBL10253332 | 0.79 | CNR2 (0.80) | EPHX2NAMPTCNR2 | |
| SCHEMBL17130471 | 0.78 | EPHX2 (1.00) | EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013065712-A1 | DIAZASPIROUREA DERIVATIVE AND PHARMACEUTICAL USE THEREOF | 東レ株式会社 (JP) | 2013-05-10 | — | — | WO | disclosed |