Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.52 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | TACR1 | P25103 | 1/20 | 0.44 |
| ▸ | RORC | P51449 | 1/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14921685 | 1.00 | GPR119 (0.52) | GPR119PDE4BKMT2ATP53TACR1 | |
| SCHEMBL14921684 | 1.00 | GPR119 (0.52) | GPR119PDE4BKMT2ATP53TACR1 | |
| SCHEMBL951033 | 0.89 | PDE4B (0.51) | GPR119PDE4BKMT2ATACR1RORC | |
| SCHEMBL14921544 | 0.89 | PDE4B (0.51) | PDE4BKMT2ASCN9A | |
| SCHEMBL14921543 | 0.89 | PDE4B (0.51) | PDE4BKMT2ASCN9A | |
| SCHEMBL16141288 | 0.89 | PDE4B (0.51) | PDE4BKMT2ASCN9A | |
| SCHEMBL16141287 | 0.89 | PDE4B (0.51) | PDE4BKMT2ASCN9A | |
| SCHEMBL12602246 | 0.89 | PDE4B (0.51) | GPR119PDE4BKMT2ATACR1RORC | |
| SCHEMBL6694614 | 0.89 | PDE4B (0.51) | GPR119PDE4BKMT2ATACR1RORC | |
| SCHEMBL3065548 | 0.89 | PDE4B (0.51) | GPR119PDE4BKMT2ATACR1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773637-B1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC (CA) | 2016-06-08 | — | — | EP | disclosed |
| WO-2013064983-A1 | BENZENESULFONAMIDE COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS | XENON PHARMACEUTICALS INC. (CA) | 2013-05-10 | — | — | WO | disclosed |