Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCB1 | P08183 | 7/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | NPC1 | O15118 | 2/20 | 0.60 |
| ▸ | RAB9A | P51151 | 2/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CES2 | O00748 | 3/20 | 0.58 |
| ▸ | MIF | P14174 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14937328 | 1.00 | ABCB1 (1.00) | ABCB1SMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL527211 | 0.90 | ABCB1 (0.82) | ABCB1SMN1; SMN2ALDH1A1LMNANPC1 | |
| SCHEMBL23761627 | 0.75 | ABCB1 (0.67) | ABCB1CES2MIF | |
| SCHEMBL29038289 | 0.74 | CES2 (0.80) | CES2MIF | |
| SCHEMBL29038294 | 0.74 | CES2 (0.80) | CES2MIF | |
| SCHEMBL28245703 | 0.74 | CES2 (1.00) | CES2MIF | |
| SCHEMBL28245700 | 0.74 | CES2 (1.00) | CES2MIF | |
| SCHEMBL4808965 | 0.74 | MIF (0.61) | ABCB1CES2MIF | |
| SCHEMBL4808970 | 0.74 | MIF (0.61) | ABCB1CES2MIF | |
| SCHEMBL28606466 | 0.73 | CES2 (0.76) | CES2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MALT1, VHL, ETV6 | ABCB1 19/4885SMN1; SMN2 3712/4885ALDH1A1 630/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.