Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939950 | 1.00 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14938946 | 1.00 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14939249 | 0.91 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14939620 | 0.89 | NPSR1 (0.68) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14939621 | 0.89 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14939917 | 0.86 | NPSR1 (0.55) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14939520 | 0.85 | NPSR1 (0.57) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14938929 | 0.85 | NPSR1 (0.56) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14938924 | 0.85 | NPSR1 (0.56) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 | |
| SCHEMBL14939630 | 0.83 | KDM4E (0.48) | NPSR1ALDH1A1ALDH3A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |