Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | FAAH | O00519 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938941 | 0.91 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14938946 | 0.91 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14939950 | 0.91 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14939620 | 0.89 | NPSR1 (0.68) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14939621 | 0.89 | NPSR1 (0.54) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14939694 | 0.86 | NPSR1 (0.73) | NPSR1ALDH1A1LMNATSHRSMN1; SMN2 | |
| SCHEMBL14939917 | 0.84 | NPSR1 (0.55) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14939520 | 0.84 | NPSR1 (0.57) | NPSR1ALDH1A1ALDH3A1NR1H4KMT2A | |
| SCHEMBL14938929 | 0.83 | NPSR1 (0.56) | NPSR1ALDH1A1ALDH3A1KMT2AMEN1 | |
| SCHEMBL14938924 | 0.83 | NPSR1 (0.56) | NPSR1ALDH1A1ALDH3A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |