SCHEMBL149390

SCHEMBL149390

Fc1[c]cc(F)c(F)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28157660 0.89
SCHEMBL3144691 0.75
SCHEMBL7215830 0.75
SCHEMBL82353 0.75
SCHEMBL21153 0.75
SCHEMBL1686040 0.75
SCHEMBL344241 0.75
SCHEMBL1039208 0.75
SCHEMBL2344889 0.75
SCHEMBL193136 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2802 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4399212-A1 SUBSTITUTED 2,3-DIHYDRO[1,3]THIAZOLO[4,5-B]PYRIDINES, SALTS THEREOF AND THEIR USE AS HERBICIDALLY ACTIVE SUBSTANCES Bayer Aktiengesellschaft (DE) 2024-07-17 EP claimed
CN-111484490-B Method suitable for large-scale production of B-RAF kinase dimer inhibitor 百济神州有限公司 2024-07-09 CN claimed
CN-118063351-B Green synthesis of chiral beta amino acids using biological enzymes and immobilized aminotransferase used 北京元延医药科技股份有限公司 2024-06-28 CN claimed
WO-2024125346-A1 PREPARATION OF DEUTERATED 4-PHENYLPIPERIDINE-4-OL COMPOUND AND USE THEREOF 南昌双天使生物科技开发有限公司 2024-06-20 WO claimed
CN-118159542-A Substituted 2, 3-dihydro [1,3] thiazolo [4,5-b ] pyridines, salts thereof and their use as herbicidal agents 拜耳公司 2024-06-07 CN claimed
CN-118063351-A Green synthesis of chiral beta amino acids using biological enzymes and immobilized aminotransferase used 北京元延医药科技股份有限公司 2024-05-24 CN claimed
CN-117447388-B Preparation and application of deuterated 4-phenylpiperidine-4-alcohol compound 南昌双天使生物科技开发有限公司 2024-05-10 CN claimed
CN-117447385-B Preparation and application of deuterated 3-aminomethyl-4-phenylpiperidin-4-ol compound 南昌双天使生物科技开发有限公司 2024-05-10 CN claimed
EP-3893645-B1 SUBSTITUTED ARYLMETHYLUREAS AND HETEROARYLMETHYLUREAS, ANALOGUES THEREOF, AND METHODS USING SAME ARBUTUS BIOPHARMA CORP (CA) 2024-04-17 EP claimed
WO-2024073282-A2 HETEROCYCLES AS MODULATORS OF NSD ACTIVITY BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-04 WO claimed
WO-1998038177-A1 HETEROCYCLIC COMPOUNDS AND THEIR USE FOR INHIBITING β-AMYLOID PEPTIDE ELAN PHARMACEUTICALS, INC. (US) 1998-09-03 WO claimed
WO-1998028268-A2 CYCLOALKYL, LACTAM, LACTONE AND RELATED COMPOUNDS AS β-AMYLOID PEPTIDE RELEASE INHIBITORS ELAN PHARMACEUTICALS, INC. (US) 1998-07-02 WO claimed
US-5574146-A Oligonucleotide synthesis with substituted aryl carboxylic acids as activators BECKMAN INSTRUMENTS, INC. (US) 1996-11-12 US claimed
EP-0654995-B1 4-OXA-1-AZABICYCLO (3,2,0) HEPTAN-7-ONE DERIVATIVES AS ANTITUMOR AGENTS TAIHO PHARMACEUTICAL CO LTD (JP) 1996-10-23 EP claimed
US-5561126-A OXAPENAMS HAVING CHEMICAL STABILITY; ANTICARCINOGENIC AGENTS; LEUKEMIA TAIHO PHARMACEUTICAL CO., LTD. (JP) 1996-10-01 US claimed
EP-0498724-B1 Esters of 3-(3,3,3-trifluoro-2-chloropropenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1996-05-15 EP claimed
EP-0654995-A1 4-OXA-1-AZABICYCLO (3,2,0) HEPTAN-7-ONE DERIVATIVES AS ANTITUMOR AGENTS. TAIHO PHARMACEUTICAL CO LTD (JP) 1995-05-31 EP claimed
WO-1994001109-A1 4-OXA-1-AZABICYCLO [3,2,0] HEPTAN-7-ONE DERIVATIVES AS ANTITUMOR AGENTS TAIHO PHARMACEUTICAL CO. LTD. (JP) 1994-01-20 WO claimed
US-5189169-A Postemergence herbicides IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-23 US claimed
EP-0498724-A1 Esters of 3-(3,3,3-trifluoro-2-chloropropenyl)-2,2-dimethyl-cyclopropanecarboxylic acid, process for their preparation and their use as pesticides ROUSSEL UCLAF (FR) 1992-08-12 EP claimed