SCHEMBL82353

SCHEMBL82353

Nc1c[c]c(F)cc1F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3718214 0.81
SCHEMBL6561427 0.79
SCHEMBL8898727 0.75
SCHEMBL10509555 0.75
SCHEMBL2318248 0.75
SCHEMBL9385771 0.75
SCHEMBL149390 0.75
SCHEMBL5843265 0.70 KHK (0.35)
SCHEMBL28272881 0.70 ALDH1A1 (0.32)
SCHEMBL28604439 0.70 ALDH1A1 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 108 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116606279-A Fluoroquinolone compound and preparation method and application thereof 广东工业大学 2023-08-18 CN claimed
US-20160045490-A1 USE OF CHEMOTHERAPEUTIC AGENTS BAYER INNOVATION GMBH (DE) 2016-02-18 US claimed
US-20140287028-A1 Use of Chemotherapeutic Agents BAYER INNOVATION GMBH (DE) 2014-09-25 US claimed
US-20070197501-A1 Use Of Chemotherapeutic Agents BAYER INNOVATION GMBH (DE) 2007-08-23 US claimed
EP-1408034-B1 Use of Quinolone and Quinolizinone derivatives as chemotherapeutic agents SCHULZ & SCHLIMBACH GBR (DE) 2007-08-08 EP claimed
CN-1668598-A Use of chemotherapeutic agents SCHULZ & SCHLIMBACH GBR (DE) 2005-09-14 CN claimed
EP-1408034-A1 Use of Quinoline derivatives as antibacterial agents Schulz &amp; Schlimbach GbR (DE) 2004-04-14 EP claimed
EP-1244434-A2 USE OF CHEMOTHERAPEUTIC AGENTS Schulz, Hans-Herrmann (DE) 2002-10-02 EP claimed
EP-0911336-B1 PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF DAINIPPON PHARMACEUTICAL CO (JP) 2001-11-28 EP claimed
WO-2001045679-A2 USE OF CHEMOTHERAPEUTIC AGENTS FOR TOPICAL TREATMENT SCHULZ HANS HERRMANN (DE) 2001-06-28 WO claimed
US-6017911-A BACTERICIDES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US claimed
EP-0911336-A1 PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1999-04-28 EP claimed
CN-111212647-B Dihydro oxadiazinones 拜耳股份有限公司 2024-05-14 CN disclosed
US-11773070-B2 Dihydrooxadiazinones BAYER AKTIENGESELLSCHAFT (DE) 2023-10-03 US disclosed
EP-3661517-B1 DIHYDROOXADIAZINONES BAYER AG (DE) 2023-09-13 EP disclosed
CN-116606279-A Fluoroquinolone compound and preparation method and application thereof 广东工业大学 2023-08-18 CN disclosed
EP-0990654-A1 SUBSTITUTED CYCLOBUTYLAMINE DERIVATIVES DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2000-04-05 EP disclosed
US-6017911-A BACTERICIDES DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 2000-01-25 US disclosed
EP-0911336-A1 PYRIDONECARBOXYLIC ACID DERIVATIVES AND INTERMEDIATES FOR THE SYNTHESIS THEREOF DAINIPPON PHARMACEUTICAL CO., LTD. (JP) 1999-04-28 EP disclosed
CN-1211986-A Pyridonecarboxylic acid derivatives and intermediates for synthesis thereof DAINIPPON PHARMACEUTICAL CO (JP) 1999-03-24 CN disclosed