Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MMP2 | P08253 | 2/20 | 0.47 |
| ▸ | MMP9 | P14780 | 2/20 | 0.47 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940444 | 0.88 | NPSR1 (0.53) | NPSR1MAPTACHELMNAALDH1A1 | |
| SCHEMBL14939694 | 0.84 | NPSR1 (0.73) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14940046 | 0.84 | NPSR1 (0.54) | NPSR1MAPTLMNAALDH1A1MEN1 | |
| SCHEMBL14939688 | 0.84 | NPSR1 (0.77) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939617 | 0.83 | NPSR1 (1.00) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939390 | 0.83 | NPSR1 (0.75) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939436 | 0.83 | NPSR1 (0.61) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939775 | 0.83 | NPSR1 (0.52) | NPSR1MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL14939178 | 0.82 | NPSR1 (0.77) | NPSR1MAPTMMP2MMP9LMNA | |
| SCHEMBL14939174 | 0.82 | NPSR1 (0.65) | NPSR1MAPTLMNAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |