Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939138 | 0.94 | NPSR1 (0.51) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939270 | 0.94 | NPSR1 (0.61) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939180 | 0.93 | NPSR1 (0.50) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14940139 | 0.93 | NPSR1 (0.51) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939962 | 0.93 | NPSR1 (0.54) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939168 | 0.92 | MAPT (0.53) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939780 | 0.92 | NPSR1 (0.44) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939615 | 0.90 | MAPT (0.53) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939335 | 0.90 | TP53 (0.48) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14940335 | 0.90 | NPSR1 (0.47) | NPSR1MAPTLMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |