Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | SMO | Q99835 | 1/20 | 0.34 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.34 |
| ▸ | UBE2M | P61081 | 1/20 | 0.33 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | FABP6 | P51161 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940185 | 0.91 | NPSR1 (0.46) | NPSR1MAPTLMNAALDH1A1GAA | |
| SCHEMBL14939978 | 0.90 | NPSR1 (0.47) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14940032 | 0.89 | NPSR1 (0.46) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14939615 | 0.88 | MAPT (0.53) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14939270 | 0.84 | NPSR1 (0.61) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14939058 | 0.83 | NPSR1 (0.43) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14940139 | 0.83 | NPSR1 (0.51) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14938918 | 0.82 | NPSR1 (0.48) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14940152 | 0.82 | NPSR1 (0.48) | NPSR1MAPTTP53LMNAALDH1A1 | |
| SCHEMBL14939842 | 0.82 | NPSR1 (0.50) | NPSR1MAPTTP53LMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |