Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939606 | 0.90 | NPSR1 (0.36) | NPSR1LMNAL3MBTL1HTTUTS2R | |
| SCHEMBL14939457 | 0.89 | NPSR1 (0.49) | NPSR1LMNAL3MBTL1HTTUTS2R | |
| SCHEMBL14939574 | 0.86 | MAPT (0.41) | NPSR1LMNAL3MBTL1HTTUTS2R | |
| SCHEMBL14938940 | 0.82 | NPSR1 (0.49) | NPSR1LMNAL3MBTL1HTTUTS2R | |
| SCHEMBL14939279 | 0.81 | NPSR1 (0.43) | NPSR1LMNAL3MBTL1HTTUTS2R | |
| SCHEMBL14939208 | 0.77 | LMNA (0.42) | NPSR1LMNAALDH1A1SMN1; SMN2HTR2A | |
| SCHEMBL14939198 | 0.77 | ESR1 (0.40) | NPSR1LMNAHTTALDH1A1SMN1; SMN2 | |
| SCHEMBL14939269 | 0.77 | LMNA (0.42) | NPSR1LMNAALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL14939614 | 0.77 | LMNA (0.37) | NPSR1LMNAMAPT | |
| SCHEMBL14939395 | 0.76 | CYP2D6 (0.41) | NPSR1LMNAL3MBTL1HTTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |