Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14938922 | 0.90 | NPSR1 (0.53) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14939378 | 0.87 | NPSR1 (0.55) | NPSR1KMT2ATP53MAPTMEN1 | |
| SCHEMBL14939417 | 0.86 | NPSR1 (0.60) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14939752 | 0.86 | MEN1 (0.55) | NPSR1KMT2ATP53MAPTMEN1 | |
| SCHEMBL14940196 | 0.86 | NPSR1 (0.70) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14939374 | 0.85 | NPSR1 (0.53) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14940008 | 0.85 | NPSR1 (0.56) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14939539 | 0.85 | NPSR1 (0.55) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14939716 | 0.85 | NPSR1 (0.50) | NPSR1KMT2ALMNATP53MAPT | |
| SCHEMBL14939117 | 0.85 | NPSR1 (0.50) | NPSR1KMT2ALMNATP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | disclosed |