Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | DRD4 | P21917 | 1/20 | 0.34 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14939725 | 0.91 | TP53 (0.47) | NPSR1MAPTTP53HTR7KDM4E | |
| SCHEMBL14939336 | 0.89 | NPSR1 (0.52) | NPSR1MAPTTP53HTR7KDM4E | |
| SCHEMBL14939242 | 0.87 | NPSR1 (0.50) | NPSR1MAPTTP53HTR7LMNA | |
| SCHEMBL14939200 | 0.87 | NPSR1 (0.53) | NPSR1MAPTTP53HTR7KDM4E | |
| SCHEMBL14939890 | 0.86 | NPSR1 (0.49) | NPSR1MAPTTP53HTR7KDM4E | |
| SCHEMBL14940534 | 0.86 | NPSR1 (0.49) | NPSR1MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL14939445 | 0.85 | TP53 (0.51) | NPSR1MAPTTP53HTR7KDM4E | |
| SCHEMBL14938832 | 0.84 | NPSR1 (0.47) | NPSR1MAPTTP53HTR7KDM4E | |
| SCHEMBL14939499 | 0.82 | NPSR1 (0.55) | NPSR1MAPTTP53KDM4EALDH1A1 | |
| SCHEMBL14939356 | 0.81 | NPSR1 (0.58) | NPSR1MAPTTP53KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |