Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 6/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 6/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.62 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.62 |
| ▸ | ESR1 | P03372 | 1/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | PGR | P06401 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.62 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1181707 | 0.93 | CYP2C9 (0.54) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL1884053 | 0.91 | CYP2C9 (0.58) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL1182267 | 0.89 | CYP2C9 (0.56) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL1182702 | 0.89 | KCNH2 (0.50) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL15277694 | 0.88 | CYP2C9 (0.57) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL1182308 | 0.87 | CYP2C9 (0.54) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL1182652 | 0.87 | CYP2C9 (0.53) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL14940602 | 0.87 | CYP2C9 (0.56) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL1182647 | 0.86 | CYP2C9 (0.53) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 | |
| SCHEMBL18856541 | 0.85 | CYP2C9 (0.53) | CYP2C9CYP2C19KCNH2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2828244-B1 | TRIAZINES WITH SUITABLE SPACERS FOR TREATMENT AND/OR PREVENTION OF HIV INFECTIONS | UNIV ANTWERPEN (BE) | 2017-11-15 | — | — | EP | disclosed |
| US-9650348-B2 | Triazines with suitable spacers for treatment and/or prevention of HIV infections | UNIVERSITEIT ANTWERPEN (BE) | 2017-05-16 | — | — | US | disclosed |
| US-9650348-B2 | Triazines with suitable spacers for treatment and/or prevention of HIV infections | UNIVERSITEIT ANTWERPEN (BE) | 2017-05-16 | — | — | US | disclosed |
| US-9650348-B2 | Triazines with suitable spacers for treatment and/or prevention of HIV infections | UNIVERSITEIT ANTWERPEN (BE) | 2017-05-16 | — | — | US | disclosed |
| US-20150126510-A1 | Triazines With Suitable Spacers for Treatment And/Or Prevention of HIV Infections | UNIVERSITEIT ANTWERPEN (BE) | 2015-05-07 | — | — | US | disclosed |
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2014-10-30 | — | — | US | disclosed |
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2014-10-30 | — | — | US | disclosed |
| EP-2776410-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | Universiteit Antwerpen (BE) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013068551-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | UNIVERSITEIT ANTWERPEN (BE) | 2013-05-16 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323488-A1 | DISUBSTITUTED TRIAZINE DIMERS FOR TREATMENT AND/OR PREVENTION OF INFECTIOUS DISEASES | TBC1D15, TBC1D5, DHFR | CYP2C9 2440/4885CYP2C19 2194/4885KCNH2 1850/4885 |
| US-20150126510-A1 | Triazines With Suitable Spacers for Treatment And/Or Prevention of HIV Infections | IKZF2, IKZF3, BAZ2A | CYP2C9 4746/4885CYP2C19 4655/4885KCNH2 2923/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.