Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 2/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14940101 | 0.91 | NPSR1 (0.48) | NPSR1MAPTCHRM3TP53LMNA | |
| SCHEMBL14940235 | 0.90 | NPSR1 (0.47) | NPSR1MAPTMEN1KMT2ATACR1 | |
| SCHEMBL14939200 | 0.88 | NPSR1 (0.53) | NPSR1MAPTTP53LMNAMEN1 | |
| SCHEMBL14939958 | 0.87 | NPSR1 (0.52) | NPSR1MAPTTP53LMNAMEN1 | |
| SCHEMBL14940182 | 0.86 | NPSR1 (0.45) | NPSR1MAPTCHRM3TP53LMNA | |
| SCHEMBL14939399 | 0.85 | NPSR1 (0.44) | NPSR1MAPTCHRM3TP53LMNA | |
| SCHEMBL14939661 | 0.83 | NPSR1 (0.55) | NPSR1MAPTCHRM3TP53LMNA | |
| SCHEMBL14940061 | 0.83 | NPSR1 (0.57) | NPSR1MAPTCHRM3TP53LMNA | |
| SCHEMBL14939244 | 0.82 | NPSR1 (0.71) | NPSR1MAPTTP53LMNAKMT2A | |
| SCHEMBL14939158 | 0.81 | NPSR1 (0.55) | NPSR1MAPTTP53LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068785-A1 | INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS | ACTELION PHARMACEUTICALS LTD (CH) | 2013-05-16 | — | — | WO | claimed |