SCHEMBL14940816

SCHEMBL14940816

CC(C)CC(NC(=O)C(N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ FOLH1 Q04609 1/20 0.69
▸ OPRD1 P41143 2/20 0.62
▸ LTA4H P09960 1/20 0.61
▸ NPY1R P25929 1/20 0.59
▸ NPY2R P49146 1/20 0.59
▸ NPY4R P50391 1/20 0.59
▸ ACE P12821 1/20 0.57
▸ MME P08473 1/20 0.56
▸ SLC7A5 Q01650 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9822809 1.00 FOLH1 (0.69) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL29532240 1.00 FOLH1 (0.69) FOLH1OPRD1LTA4HNPY1RNPY2R
Hydrochloric Acid SCHEMBL30698091 0.99 FOLH1 (0.67) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL29477112 0.97 FOLH1 (0.66) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL30683246 0.97 FOLH1 (0.66) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL29531738 0.97 FOLH1 (0.66) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL29822390 0.96 FOLH1 (0.68) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL3059716 0.94 FOLH1 (0.62) FOLH1OPRD1LTA4HNPY1RNPY2R
SCHEMBL3059707 0.94 FOLH1 (0.62) FOLH1OPRD1LTA4HNPY1RNPY2R
Trifluoroacetic Acid SCHEMBL2197916 0.94 FOLH1 (0.62) FOLH1OPRD1LTA4HNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022149634-A1 COLOR COSMETIC COMPOSITION CONTAINING COLOR BASE AND EXTRACT ENZYMATICALLY REACTED AT LOW TEMPERATURE AND HIGH PRESSURE (주)비엔 2022-07-14 — — WO claimed
US-12259397-B2 Biomarkers related to organ function University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2025-03-25 — — US disclosed
WO-2024224093-A1 DESMURAMYLPEPTIDE DIEESTERS AS NOD2 AGONISTS AND USE THEREOF Imhotex Limited (GB) 2024-10-31 — — WO disclosed
CN-116514919-A Targeted antagonistic peptide for inhibiting tumor growth and angiogenesis and application thereof 浙江清华长三角研究院 2023-08-01 — — CN disclosed
US-11351268-B2 FGF21 C-terminal peptide optimization INDIANA UNIVERSITY RESEARCH AND TECHNOLOGY CORPORATION (US) 2022-06-07 — — US disclosed
US-20200284805-A1 BIOMARKERS RELATED TO ORGAN FUNCTION UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2020-09-10 — — US disclosed
US-10634686-B2 Biomarkers related to organ function University of Pittsburgh—of the Commonwealth System of Higher Education (US) 2020-04-28 — — US disclosed
US-20160231330-A1 BIOMARKERS RELATED TO ORGAN FUNCTION UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2016-08-11 — — US disclosed
US-20160128961-A1 DIETARY OMEGA-3 FATTY ACID DERIVED GLYCEROPHOSPHOLIPIDS TO TREAT NEUROPATHIC PAIN UNIV LOMA LINDA (US) 2016-05-12 — — US disclosed
WO-2015042602-A1 BIOMARKERS RELATED TO ORGAN FUNCTION UNIVERSITY OF PITTSBURGH-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2015-03-26 — — WO disclosed
US-20150065366-A1 Biomarkers for Bladder Cancer and Methods Using the Same METABOLON, INC. 2015-03-05 — — US disclosed
US-20140343865-A1 Biomarkers for Kidney Cancer and Methods Using the Same METABOLON, INC. 2014-11-20 — — US disclosed
EP-2788763-A2 BIOMARKERS FOR KIDNEY CANCER AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-10-15 — — EP disclosed
US-20140296134-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2014-10-02 — — US disclosed
EP-2776829-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION The Board of Regents of The University of Texas System (US) 2014-09-17 — — EP disclosed
EP-2776832-A1 BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-09-17 — — EP disclosed
WO-2013086365-A2 BIOMARKERS FOR KIDNEY CANCER AND METHODS USING THE SAME METABOLON, INC. (US) 2013-06-13 — — WO disclosed
WO-2013070962-A1 METHODS AND USES FOR METABOLIC PROFILING FOR CLOSTRIDIUM DIFFICILE INFECTION THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2013-05-16 — — WO disclosed
WO-2013070839-A1 BIOMARKERS FOR BLADDER CANCER AND METHODS USING THE SAME METABOLON, INC. (US) 2013-05-16 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11351268-B2 FGF21 C-terminal peptide optimization FGF23, FGFR1, FGFR3 FOLH1 175/4885OPRD1 3847/4885LTA4H 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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