Succimer

Succimer

SCHEMBL14941

O=C(O)[C@@H](S)[C@@H](S)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 1.00
HPGD P15428 2/20 1.00
HSD17B10 Q99714 2/20 1.00
TDP1 Q9NUW8 2/20 1.00
LMNA P02545 2/20 1.00
ABCB11 O95342 1/20 1.00
F2 P00734 1/20 1.00
KDM4E B2RXH2 1/20 1.00
MEN1 O00255 1/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
KMT2A Q03164 1/20 1.00
DUSP3 P51452 1/20 1.00
PTPN5 P54829 1/20 1.00
PTPN11 Q06124 1/20 1.00
CYP2C9 P11712 1/20 1.00
HIF1A Q16665 1/20 1.00
TSHR P16473 1/20 0.40
THRB P10828 1/20 0.40
RECQL P46063 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Succimer SCHEMBL28566852 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL17472961 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL14942 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL28577215 1.00 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL23522179 0.96 ALDH1A1 (0.92) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL31037952 0.96 ALDH1A1 (0.92) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL30951062 0.96 ALDH1A1 (0.92) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL10797056 0.96 ALDH1A1 (0.92) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL2771039 0.96 ALDH1A1 (0.92) ALDH1A1HPGDHSD17B10TDP1LMNA
Succimer SCHEMBL4647017 0.96 ALDH1A1 (0.92) ALDH1A1HPGDHSD17B10TDP1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 13046 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122094309-A Optoelectronic device and method for producing the same 2026-05-26 CN claimed
WO-2026105128-A1 MESO-2,3-DIMERCAPTOSUCCINIC ACID (DMSA)-CONJUGATED NUCLEOTIDE-BASED AGENTS HAVING IMPROVED DELIVERY TO KIDNEY TISSUE Sheba Impact Ltd. (IL) 2026-05-21 WO claimed
US-20260139183-A1 Chelating Compositions and Methods of Use LOCUS SOLUTIONS IPCO LLC (US) 2026-05-21 US claimed
CN-122045631-A Physical-data fusion filling method, equipment and medium based on sparse gating 安徽大学 2026-05-15 CN claimed
CN-121182437-B Ultraviolet light curing composition for prismatic film with transverse grain structure and preparation method thereof 上海绘兰材料科技有限公司 2026-05-15 CN claimed
US-20260130847-A1 INGESTIBLE IN VIVO-ASSEMBLING DRUG RELEASE FORMULATIONS AND METHODS MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2026-05-14 US claimed
EP-4739291-A2 ADMINISTRATION OF KERATOLYTICS TO OCULAR AND PERIOCULAR SURFACES AZURA OPHTHALMICS LTD (IL) 2026-05-13 EP claimed
EP-4741492-A2 NECROSIS INHIBITOR Linkgevity Limited (GB) 2026-05-13 EP claimed
EP-4739293-A2 COMPOSITIONS AND METHODS FOR THE TREATMENT OF AUTOIMMUNE DISORDERS AZURA OPHTHALMICS LTD (IL) 2026-05-13 EP claimed
CN-122016687-A Silver metallized microbubbles in Hg2+Detection and application of alloy microbubble nano enzyme prepared by detection in detection of reducing drugs 广西医科大学 2026-05-12 CN claimed
EP-0224246-A2 Process for preparing 3-chloro-1, 2-propanediol KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1987-06-03 EP claimed
CN-86104557-A Adopt photosensitive microcapsules to contain the image forming material of tertiary amines as coinitiators 1987-04-22 CN claimed
WO-1986001410-A1 ANTIBODY-METAL ION COMPLEXES CYTOGEN CORPORATION (US) 1986-03-13 WO claimed
EP-0173629-A1 Antibody-metal ion complexes CYTOGEN CORPORATION (US) 1986-03-05 EP claimed
WO-1985003063-A1 PREPARATION OF 99mTC RADIOPHARMACEUTICALS THE COMMONWEALTH OF AUSTRALIA (AU) 1985-07-18 WO claimed
US-4364920-A Stable diagnostic reagents MEDI-PHYSICS, INC. (US) 1982-12-21 US claimed
US-4208398-A COMPLEXED WITH MERCAPTANS, KIDNEY SPECIFIC HOFFMAN-LA ROCHE INC. (US) 1980-06-17 US claimed
US-3995020-A Radioactive erbium-165 complexes and methods of preparation and use thereof ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 1976-11-30 US claimed
US-3984522-A Method of removing nitrogen monoxide from a nitrogen monoxide-containing gas ASAHI KASEI KOGYO KABUSHIKI KAISHA (JA) 1976-10-05 US claimed
US-3943100-A THIOMALIC, DIMERCAPTOSUCCINIC, GALLIC, CITRIC OR TARTARIC ACID OR SALTS ALLIED CHEMICAL CORPORATION (US) 1976-03-09 US claimed