Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.37 |
| ▸ | MME | P08473 | 3/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25288139 | 0.78 | CYP2C19 (0.48) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL5511328 | 0.78 | CYP2C19 (0.48) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL5510502 | 0.76 | CYP2C19 (0.45) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL5608513 | 0.75 | CYP1A2 (0.47) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL28178666 | 0.74 | CYP2C19 (0.44) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL7770551 | 0.72 | CYP1A2 (0.44) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL7772817 | 0.72 | CYP1A2 (0.44) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL7768488 | 0.72 | CYP1A2 (0.44) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL10488668 | 0.71 | CA2 (0.42) | CYP2C19CYP1A2ALDH1A1USP2LMNA | |
| SCHEMBL5510045 | 0.71 | CYP2C19 (0.40) | CYP2C19CYP1A2ALDH1A1USP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2775906-A1 | EVALUATION OF PRESENCE OF AND VULNERABILITY TO ATRIAL FIBRILLATION AND OTHER INDICATIONS USING MATRIX METALLOPROTEINASE-BASED IMAGING | Lantheus Medical Imaging, Inc. (US) | 2014-09-17 | — | — | EP | disclosed |
| WO-2013070471-A1 | EVALUATION OF PRESENCE OF AND VULNERABILITY TO ATRIAL FIBRILLATION AND OTHER INDICATIONS USING MATRIX METALLOPROTEINASE-BASED IMAGING | LANTHEUS MEDICAL IMAGING, INC. (US) | 2013-05-16 | — | — | WO | disclosed |