Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 10/20 | 0.36 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | CLK1 | P49759 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14943012 | 0.94 | AR (0.36) | ARPLA2G7 | |
| SCHEMBL13032081 | 0.93 | TRPV4 (0.36) | ARPLA2G7 | |
| SCHEMBL14931299 | 0.90 | AR (0.32) | ARPLA2G7 | |
| SCHEMBL14943014 | 0.90 | AR (0.36) | ARPLA2G7 | |
| SCHEMBL16684156 | 0.89 | TRPV4 (0.34) | ARPLA2G7 | |
| SCHEMBL14943020 | 0.89 | TRPV4 (0.34) | ARPLA2G7 | |
| SCHEMBL14943032 | 0.89 | TRPV4 (0.37) | — | |
| SCHEMBL14943071 | 0.89 | AR (0.36) | ARPLA2G7 | |
| SCHEMBL16684163 | 0.88 | AR (0.33) | AR | |
| SCHEMBL14943084 | 0.88 | AR (0.35) | ARPLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8440643-B2 | Inhibitors of beta-lactamase | METHYLGENE INC. (CA) | 2013-05-14 | — | — | US | disclosed |