Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 6/20 | 0.32 |
| ▸ | MMP12 | P39900 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAPDH | P04406 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.31 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7922402 | 0.78 | CREBBP (0.39) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL18708715 | 0.77 | BRD4 (0.35) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL13866108 | 0.76 | BRD4 (0.37) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL27590553 | 0.73 | BRD4 (0.36) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL12984932 | 0.71 | PARP1 (0.41) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL22791448 | 0.67 | CREBBP (0.46) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL9845271 | 0.67 | AR (0.41) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL7345041 | 0.67 | CREBBP (0.46) | BRD4CREBBPALDH1A1MAPTHSD17B10 | |
| SCHEMBL27280283 | 0.66 | USP2 (0.32) | BRD4CREBBPHSD17B10GAAALOX15 | |
| SCHEMBL21693359 | 0.66 | BRD4 (0.34) | BRD4CREBBPHPGDKMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2592073-A2 | Human protein tyrosine phosphatase inhibitors and their use | Warner Chilcott Company, LLC (PR) | 2013-05-15 | — | — | EP | disclosed |