SCHEMBL9845271

SCHEMBL9845271

Cc1ccc2c(c1)OCC(C)N2

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AR P10275 2/20 0.41
CYP19A1 P11511 2/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 3/20 0.39
HSD17B10 Q99714 3/20 0.39
GAA P10253 2/20 0.39
MMP12 P39900 1/20 0.37
BRD4 O60885 1/20 0.36
CREBBP Q92793 1/20 0.36
CA2 P00918 1/20 0.35
KDM4E B2RXH2 2/20 0.33
HPGD P15428 2/20 0.33
ALOX15 P16050 2/20 0.33
MEN1 O00255 1/20 0.32
GAPDH P04406 1/20 0.32
POLB P06746 1/20 0.32
HSPA1A P0DMV8 1/20 0.32
APEX1 P27695 1/20 0.32
PTPN7 P35236 1/20 0.32
BRCA1 P38398 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3885063 0.86 ALDH1A1 (0.50) ARCYP19A1ALDH1A1MAPTHSD17B10
SCHEMBL31451387 0.86 ALDH1A1 (0.50) ARCYP19A1ALDH1A1MAPTHSD17B10
SCHEMBL23323049 0.83 GAA (0.44) CYP19A1ALDH1A1MAPTHSD17B10GAA
SCHEMBL8641161 0.81 BRD4 (0.44) ARBRD4CREBBP
SCHEMBL20798244 0.81 KDM4E (0.41) ARCYP19A1ALDH1A1HSD17B10CA2
SCHEMBL10494909 0.81 AR (0.40) ARCYP19A1ALDH1A1MAPTHSD17B10
SCHEMBL10197527 0.81 AR (0.40) ARCYP19A1MAPTBRD4CA2
SCHEMBL23920052 0.81 KDM4E (0.41) ARCYP19A1ALDH1A1HSD17B10CA2
SCHEMBL20888295 0.81 CYP19A1 (0.38) CYP19A1ALDH1A1MAPTHSD17B10GAA
SCHEMBL23920054 0.81 KDM4E (0.41) ARCYP19A1ALDH1A1HSD17B10CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230028644-A1 Low Greenhouse Gas Fuel Compositions BP OIL INTERNATIONAL LIMITED (GB) 2023-01-26 US disclosed
US-11384057-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
US-11384302-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-07-12 US disclosed
EP-3414305-B1 FUEL COMPOSITIONS BP OIL INT (GB) 2022-06-15 EP disclosed
US-11359151-B2 Methods for preparing fuel additives BP OIL INTERNATIONAL LIMITED (GB) 2022-06-14 US disclosed
US-11339343-B2 Methods for blending fuels BP OIL INTERNATIONAL LIMITED (GB) 2022-05-24 US disclosed
US-11332682-B2 Methods for reducing oxidation BP OIL INTERNATIONAL LIMITED (GB) 2022-05-17 US disclosed
EP-3414303-B1 USES OF ADDITIVES FOR DEMULSIFYING BP OIL INT (GB) 2022-01-26 EP disclosed
US-20210171849-A1 METHODS FOR CONTROLLING DEPOSITS BP OIL INTERNATIONAL LIMITED (GB) 2021-06-10 US disclosed
US-20210139800-A1 METHODS FOR REDUCING OXIDATION BP OIL INTERNATIONAL LIMITED (GB) 2021-05-13 US disclosed
WO-2017137519-A1 FUEL COMPOSITIONS WITH ADDITIVES BP OIL INTERNATIONAL LIMITED (GB) 2017-08-17 WO disclosed
EP-3205704-A1 METHODS FOR DEMULSIFYING BP OIL INTERNATIONAL LIMITED (GB) 2017-08-16 EP disclosed
EP-3205702-A1 FUEL COMPOSITIONS WITH ADDITIVES BP OIL INTERNATIONAL LIMITED (GB) 2017-08-16 EP disclosed
EP-3205701-A1 FUEL COMPOSITIONS BP OIL INTERNATIONAL LIMITED (GB) 2017-08-16 EP disclosed
EP-3205703-A1 FUEL ADDITIVES BP OIL INTERNATIONAL LIMITED (GB) 2017-08-16 EP disclosed
EP-3205700-A1 ADDITISING A FUEL BP OIL INTERNATIONAL LIMITED (GB) 2017-08-16 EP disclosed
EP-3205706-A1 METHODS FOR REDUCING FERROUS CORROSION BP OIL INTERNATIONAL LIMITED (GB) 2017-08-16 EP disclosed
EP-0437105-A1 Intermediates and colorants having primary hydroxyl enriched poly(oxyalkylene) moieties and their preparation MILLIKEN RESEARCH CORPORATION (US) 1991-07-17 EP disclosed
US-4288589-A Cationic dyes CIBA-GEIGY CORPORATION (US) 1981-09-08 US disclosed
US-3984548-A Substituted pyrido[1,2,3,-de]-1,4-benzoxazines as bactericides RIKER LABORATORIES, INC. (US) 1976-10-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11384057-B2 Methods for preparing fuel additives POLB, IDH2, TOP2B AR 1962/4885CYP19A1 261/4885ALDH1A1 264/4885
US-11359151-B2 Methods for preparing fuel additives GSDMD, SCD, FADS1 AR 1044/4885CYP19A1 270/4885ALDH1A1 1572/4885
US-11384302-B2 Methods for preparing fuel additives GSDMD, DEGS1, SCD AR 1598/4885CYP19A1 412/4885ALDH1A1 1552/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.