Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR4 | P61073 | 2/20 | 0.55 |
| ▸ | GNAO1 | P09471 | 5/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.42 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | SOD3 | P08294 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21016068 | 1.00 | CXCR4 (0.55) | CXCR4GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL11932527 | 0.98 | CXCR4 (0.52) | CXCR4GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL13251374 | 0.92 | CXCR4 (0.50) | CXCR4GNAO1GNAI3GNAI1SIGMAR1 | |
| Hydrochloric Acid SCHEMBL27423153 | 0.90 | CXCR4 (0.48) | CXCR4GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL21015652 | 0.86 | CXCR4 (0.42) | CXCR4GNAO1GNAI3GNAI1SIGMAR1 | |
| SCHEMBL1810789 | 0.85 | HRH3 (0.46) | GNAO1GNAI3GNAI1SMN1; SMN2HRH3 | |
| SCHEMBL21016198 | 0.84 | CXCR4 (0.41) | CXCR4SIGMAR1HRH3GBA1KDM4E | |
| SCHEMBL104625 | 0.83 | SMN1; SMN2 (0.45) | CXCR4SIGMAR1POLBSMN1; SMN2CHRM5 | |
| SCHEMBL26375600 | 0.83 | LMNA (0.43) | GNAO1GNAI3GNAI1SIGMAR1SMN1; SMN2 | |
| SCHEMBL11726023 | 0.82 | CXCR4 (0.74) | CXCR4GNAO1GNAI3GNAI1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190151403-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | S&T GLOBAL INC. | 2019-05-23 | — | — | US | disclosed |
| EP-1723105-B1 | BICYCLIC SUBSTITUTED INDOLE-DERIVATIVE STEROID HORMONE NUCLEAR RECEPTOR MODULATORS | LILLY CO ELI (US) | 2013-05-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190151403-A1 | NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF | MALT1, MYLK2, FKBP1B | CXCR4 3546/4885GNAO1 4450/4885GNAI3 2809/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.