Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1571399 | 0.91 | CCR2 (0.73) | CCR2 | |
| SCHEMBL8985586 | 0.91 | CCR2 (0.73) | CCR2 | |
| SCHEMBL8985746 | 0.90 | CCR2 (0.65) | CCR2 | |
| SCHEMBL8985396 | 0.87 | CCR2 (0.67) | CCR2 | |
| SCHEMBL9049916 | 0.79 | CCR2 (0.71) | CCR2 | |
| SCHEMBL1570428 | 0.79 | CCR2 (0.83) | CCR2 | |
| SCHEMBL1570431 | 0.79 | CCR2 (0.83) | CCR2 | |
| SCHEMBL8985759 | 0.78 | CCR2 (0.73) | CCR2 | |
| SCHEMBL10066738 | 0.77 | CCR2 (1.00) | CCR2 | |
| SCHEMBL13596370 | 0.77 | CCR2 (1.00) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2307363-B1 | PIPERIDYL ACRYLAMIDE ANTAGONISTS OF CCR2 | JANSSEN PHARMACEUTICA NV (BE) | 2013-05-15 | — | — | EP | disclosed |