SCHEMBL14944652

SCHEMBL14944652

CC1C(O)CC(O)(C(=O)OCc2ccccc2)OC1C(O)C(O)CO

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 1/20 0.47
▸ MAG P20916 4/20 0.38
▸ CD22 P20273 5/20 0.36
▸ DDB1 Q16531 1/20 0.35
▸ CRBN Q96SW2 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.34
▸ HTR2C P28335 1/20 0.34
▸ CYP1A2 P05177 1/20 0.33
▸ CYP3A4 P08684 1/20 0.33
▸ CYP2D6 P10635 1/20 0.33
▸ CYP2C9 P11712 1/20 0.33
▸ CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16348268 0.88 L3MBTL1 (0.45) L3MBTL1MAGCD22DDB1CRBN
SCHEMBL17546165 0.88 L3MBTL1 (0.45) L3MBTL1MAGCD22DDB1CRBN
SCHEMBL28320235 0.88 L3MBTL1 (0.45) L3MBTL1MAGCD22DDB1CRBN
SCHEMBL10084278 0.88 L3MBTL1 (0.45) L3MBTL1MAGCD22DDB1CRBN
SCHEMBL20305857 0.87 L3MBTL1 (0.40) L3MBTL1MAGCD22ALDH1A1HTR2C
SCHEMBL14946228 0.85 MAG (0.52) L3MBTL1MAGCD22
SCHEMBL30481193 0.85 MAG (0.52) L3MBTL1MAGCD22
SCHEMBL31500844 0.85 MAG (0.52) L3MBTL1MAGCD22
SCHEMBL27977966 0.85 MAG (0.52) L3MBTL1MAGCD22
SCHEMBL25702221 0.85 MAG (0.52) L3MBTL1MAGCD22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160297846-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL INC. (US) 2016-10-13 — — US disclosed
US-8840926-B2 Sialic acid analogs ULTRAGENYX PHARMACEUTICAL INC. (US) 2014-09-23 — — US disclosed
US-20130122094-A1 SIALIC ACID ANALOGS ULTRAGENYX PHARMACEUTICAL, INC. (US) 2013-05-16 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160297846-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 L3MBTL1 1717/4885MAG 768/4885CD22 108/4885
US-20130122094-A1 SIALIC ACID ANALOGS NEU1, NEU2, NEU3 L3MBTL1 1717/4885MAG 768/4885CD22 108/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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