Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 18/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206183 | 0.90 | TLR7 (0.42) | TLR7NUDT1ADORA1 | |
| SCHEMBL20343763 | 0.79 | TLR7 (0.42) | TLR7NUDT1ADORA1 | |
| SCHEMBL14944659 | 0.78 | TLR7 (0.62) | TLR7NUDT1ADORA1 | |
| SCHEMBL19423908 | 0.76 | TLR7 (0.50) | TLR7NUDT1ADORA1 | |
| SCHEMBL14944710 | 0.76 | TLR7 (0.69) | TLR7NUDT1ADORA1 | |
| SCHEMBL16206192 | 0.76 | TLR7 (0.51) | TLR7ADORA1 | |
| SCHEMBL14944673 | 0.75 | TLR7 (0.64) | TLR7NUDT1ADORA1 | |
| SCHEMBL14944614 | 0.75 | TLR7 (0.51) | TLR7ADORA1 | |
| SCHEMBL16206187 | 0.73 | TLR7 (0.48) | TLR7NUDT1ADORA1 | |
| SCHEMBL14944683 | 0.73 | TLR7 (0.65) | TLR7NUDT1ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |