Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.49 |
| ▸ | IL6 | P05231 | 9/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14944710 | 0.84 | TLR7 (0.69) | TLR7ADORA1 | |
| SCHEMBL14944659 | 0.82 | TLR7 (0.62) | TLR7ADORA1 | |
| SCHEMBL14944707 | 0.79 | TLR7 (0.43) | TLR7ADORA1 | |
| SCHEMBL14944614 | 0.77 | TLR7 (0.51) | TLR7ADORA1IL6 | |
| SCHEMBL16206187 | 0.77 | TLR7 (0.48) | TLR7ADORA1 | |
| SCHEMBL19423908 | 0.77 | TLR7 (0.50) | TLR7ADORA1 | |
| SCHEMBL16206183 | 0.77 | TLR7 (0.42) | TLR7ADORA1 | |
| SCHEMBL14944712 | 0.76 | TLR7 (0.44) | TLR7ADORA1 | |
| SCHEMBL20343763 | 0.76 | TLR7 (0.42) | TLR7ADORA1 | |
| SCHEMBL14944683 | 0.75 | TLR7 (0.65) | TLR7ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9556176-B2 | Purine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2017-01-31 | — | — | US | disclosed |
| US-20140323441-A1 | Purine derivatives for the treatment of viral infections | JANSSEN SCIENCES IRELAND UC (IE) | 2014-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140323441-A1 | Purine derivatives for the treatment of viral infections | PNP, HPRT1, TYMP | TLR7 217/4885ADORA1 28/4885IL6 429/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.