Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 5/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 10/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.35 |
| ▸ | MTOR | P42345 | 2/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PARG | Q86W56 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206182 | 0.85 | TLR7 (0.54) | TLR7ADORA1 | |
| SCHEMBL14944686 | 0.75 | TLR7 (0.33) | TLR7ADORA1 | |
| SCHEMBL14944728 | 0.72 | TLR7 (0.61) | TLR7 | |
| SCHEMBL16206185 | 0.72 | TLR7 (0.61) | TLR7 | |
| SCHEMBL14944656 | 0.68 | TLR7 (0.53) | TLR7KMT2A | |
| SCHEMBL20343744 | 0.68 | TLR7 (0.32) | TLR7ADORA1 | |
| SCHEMBL14944679 | 0.66 | TLR7 (0.38) | TLR7 | |
| SCHEMBL19419442 | 0.66 | ADORA2A (0.49) | TLR7ADORA2AADORA1 | |
| SCHEMBL14944620 | 0.66 | TLR7 (0.59) | TLR7ADORA1 | |
| SCHEMBL14944681 | 0.63 | TLR7 (0.55) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |