Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 8/20 | 0.33 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16206182 | 0.76 | TLR7 (0.54) | TLR7ADORA1 | |
| SCHEMBL14944753 | 0.75 | USP1 (0.39) | TLR7ADORA1 | |
| SCHEMBL19423858 | 0.67 | CCR5 (0.31) | TLR7 | |
| SCHEMBL14944658 | 0.66 | TLR7 (0.36) | TLR7ADORA1 | |
| SCHEMBL20343744 | 0.66 | TLR7 (0.32) | TLR7ADORA1 | |
| SCHEMBL16206185 | 0.65 | TLR7 (0.61) | TLR7 | |
| SCHEMBL28184098 | 0.61 | MAPK1 (0.39) | TLR7 | |
| SCHEMBL20343748 | 0.59 | GSK3A (0.43) | TLR7 | |
| SCHEMBL19423898 | 0.59 | GSK3B (0.32) | TLR7 | |
| SCHEMBL28183235 | 0.58 | MAPK1 (0.38) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013068438-A1 | PURINE DERIVATIVES FOR THE TREATMENT OF VIRAL INFECTIONS | JANSSEN R&D IRELAND (IE) | 2013-05-16 | — | — | WO | disclosed |