Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13879037 | 0.89 | THRB (0.53) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL13401005 | 0.86 | TSHR (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL182045 | 0.82 | TSHR (0.72) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL9162964 | 0.80 | TSHR (0.69) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL11600594 | 0.80 | TSHR (0.69) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL18101451 | 0.78 | TSHR (0.67) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL25426 | 0.78 | TSHR (0.79) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL5144090 | 0.78 | TSHR (0.79) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL3871346 | 0.78 | THRB (0.58) | TSHRTHRBALDH1A1POLBAPEX1 | |
| SCHEMBL22726277 | 0.78 | TSHR (0.53) | TSHRTHRBALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |