Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | MYC | P01106 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 3/20 | 0.37 |
| ▸ | CA1 | P00915 | 3/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA7 | P43166 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5164883 | 0.88 | POLB (0.44) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL29757196 | 0.88 | TSHR (0.46) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL930924 | 0.88 | TSHR (0.46) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL14944800 | 0.86 | POLB (0.39) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL18812871 | 0.85 | TDP1 (0.53) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL28886899 | 0.82 | TSHR (0.53) | TSHRALDH1A1MAPK1TDP1CA2 | |
| SCHEMBL14262501 | 0.81 | POLB (0.49) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL14262508 | 0.81 | TDP1 (0.49) | TSHRALDH1A1MAPK1POLBAPEX1 | |
| SCHEMBL13171716 | 0.81 | MAPT (0.43) | TSHRALDH1A1POLBAPEX1HTT | |
| SCHEMBL643444 | 0.80 | THRB (0.47) | TSHRALDH1A1MAPK1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9217109-B2 | Polymer-stabilised liquid-crystal media and displays | MERCK PATENT GMBH (DE) | 2015-12-22 | — | — | US | disclosed |
| US-20130119311-A1 | POLYMER-STABILISED LIQUID-CRYSTAL MEDIA AND DISPLAYS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-05-16 | — | — | US | disclosed |