Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 4/20 | 0.44 |
| ▸ | NCF1 | P14598 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PTK2B | Q14289 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | AKT2 | P31751 | 3/20 | 0.39 |
| ▸ | AKT3 | Q9Y243 | 3/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1662034 | 0.86 | LOXL2 (0.53) | LOXL2CYP1A2AKT1NCF1MAPT | |
| SCHEMBL29556980 | 0.86 | LOXL2 (0.53) | LOXL2CYP1A2AKT1NCF1MAPT | |
| SCHEMBL503049 | 0.86 | LOXL2 (0.53) | LOXL2CYP1A2AKT1NCF1MAPT | |
| SCHEMBL503050 | 0.86 | LOXL2 (0.53) | LOXL2CYP1A2AKT1NCF1MAPT | |
| SCHEMBL6245559 | 0.84 | LOXL2 (0.47) | LOXL2CYP1A2AKT1NCF1FAAH | |
| SCHEMBL6245556 | 0.84 | LOXL2 (0.47) | LOXL2CYP1A2AKT1NCF1FAAH | |
| SCHEMBL6495560 | 0.84 | LOXL2 (0.47) | LOXL2CYP1A2AKT1NCF1MAPT | |
| Hydrochloric Acid SCHEMBL6495563 | 0.83 | LOXL2 (0.46) | LOXL2CYP1A2AKT1NCF1MAPT | |
| Hydrochloric Acid SCHEMBL6495555 | 0.83 | LOXL2 (0.46) | LOXL2CYP1A2AKT1NCF1MAPT | |
| SCHEMBL13957539 | 0.83 | LOXL2 (0.46) | LOXL2CYP1A2AKT1MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | LOXL2 2215/4885CYP1A2 4100/4885AKT1 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.