Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 4/20 | 0.78 |
| ▸ | GRIA3 | P42263 | 4/20 | 0.78 |
| ▸ | GRIA2 | P42262 | 3/20 | 0.78 |
| ▸ | GRIA4 | P48058 | 3/20 | 0.78 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GRIK1 | P39086 | 2/20 | 0.44 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.44 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.44 |
| ▸ | GRIK4 | Q16099 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13957545 | 1.00 | GRIA1 (0.78) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL2036596 | 0.87 | GRIA1 (1.00) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL2036595 | 0.87 | GRIA1 (1.00) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7159018 | 0.84 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7168351 | 0.84 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7159013 | 0.84 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7167715 | 0.84 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7167719 | 0.84 | GRIA1 (0.71) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7162885 | 0.84 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A | |
| SCHEMBL7162867 | 0.84 | GRIA1 (0.56) | GRIA1GRIA3GRIA2GRIA4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | SEATTLE GENETICS, INC. (US) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123465-A1 | MONOMETHYLVALINE COMPOUNDS HAVING PHENYLALANINE SIDE-CHAIN MODIFICATIONS AT THE C-TERMINUS | MMAB, PTMS, DNPEP | GRIA1 1644/4885GRIA3 1910/4885GRIA2 1898/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.