SCHEMBL2036596

SCHEMBL2036596

Cc1onc(OCC(=O)O)c1CC(N)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 4/20 1.00
GRIA3 P42263 4/20 1.00
GRIA2 P42262 3/20 1.00
GRIA4 P48058 3/20 1.00
HIF1A Q16665 1/20 0.50
BLM P54132 1/20 0.50
MAPT P10636 2/20 0.47
GRIK1 P39086 2/20 0.47
GRIK5 Q16478 2/20 0.47
MEN1 O00255 1/20 0.47
ALDH1A1 P00352 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2D6 P10635 1/20 0.47
CYP2C9 P11712 1/20 0.47
TSHR P16473 1/20 0.47
CYP2C19 P33261 1/20 0.47
KMT2A Q03164 1/20 0.47
GRIK2 Q13002 1/20 0.47
GRIK3 Q13003 1/20 0.47
GRIK4 Q16099 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2036595 1.00 GRIA1 (1.00) GRIA1GRIA3GRIA2GRIA4HIF1A
SCHEMBL13957545 0.87 GRIA1 (0.78) GRIA1GRIA3GRIA2GRIA4HIF1A
SCHEMBL14945013 0.87 GRIA1 (0.78) GRIA1GRIA3GRIA2GRIA4HIF1A
SCHEMBL7167719 0.83 GRIA1 (0.71) GRIA1GRIA3GRIA2GRIA4HIF1A
SCHEMBL7167715 0.83 GRIA1 (0.71) GRIA1GRIA3GRIA2GRIA4HIF1A
SCHEMBL8812978 0.77 GRIA1 (0.71) GRIA1GRIA3GRIA2GRIA4BLM
SCHEMBL8812980 0.77 GRIA1 (0.71) GRIA1GRIA3GRIA2GRIA4BLM
(R,S)-Ampa SCHEMBL2458874 0.76 GRIA1 (0.69) GRIA1GRIA3GRIA2GRIA4HIF1A
(R,S)-Ampa SCHEMBL68799 0.76 GRIA1 (0.69) GRIA1GRIA3GRIA2GRIA4HIF1A
(S)-Ampa SCHEMBL667915 0.76 GRIA1 (0.69) GRIA1GRIA3GRIA2GRIA4HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 189 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120875604-B Intelligent evaluation system and method for soil ecological function 广西壮族自治区国有七坡林场 2026-05-12 CN claimed
CN-118599738-B Preparation method of organic contaminated soil carbon fixation and decontamination functional flora 南京农业大学 2025-01-03 CN claimed
CN-118599738-A Preparation method of organic contaminated soil carbon fixation and decontamination functional flora 南京农业大学 2024-09-06 CN claimed
CN-118388028-A Method for realizing shortcut nitrification starting and maintaining by combining hydroxylamine with high-dissolved oxygen to inhibit nitrite oxidizing bacteria and whole-process ammonia oxidizing bacteria 生态环境部土壤与农业农村生态环境监管技术中心 2024-07-26 CN claimed
CN-114350763-B Method for identifying nitrifying microorganism 中国科学院城市环境研究所 2024-04-30 CN claimed
CN-117343914-B Modified ammonia monooxygenase, carrier, microorganism and method for ammonia nitrogen degradation 四川水王子环境科技有限公司 2024-02-20 CN claimed
CN-117467780-A Determination method of heterotrophic nitrification-aerobic denitrification bacterial nitrogen metabolic pathway 浙江大学 2024-01-30 CN claimed
CN-117343914-A Modified ammonia monooxygenase, carrier, microorganism and method for ammonia nitrogen degradation 四川水王子环境科技有限公司 2024-01-05 CN claimed
US-11834737-B2 Titanium alloy coating film and titanium alloy target material DAIDO STEEL CO., LTD. (JP) 2023-12-05 US claimed
CN-113189291-B Natural water system water quality condition assessment method and application thereof 广州绿曦生物科技有限公司 2023-10-27 CN claimed
CN-112951330-B Method for obtaining relative abundance and activity of whole-course ammonia oxidizing microorganisms from complex environment system based on macro-composition technology 北京大学 2022-09-27 CN claimed
WO-2011076946-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF ALZHEIMER Universidad Del País Vasco (ES) 2011-06-30 WO claimed
US-7101879-B2 Treatments for neurotoxicity in Alzheimer's Disease MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2006-09-05 US claimed
US-20040152694-A1 Methods and compositions for treating inflammatory disorders of the airways IVAX DRUG RESEARCH INSTITUTE, LTD. 2004-08-05 US claimed
EP-1015013-A4 TREATMENTS FOR NEUROTOXICITY IN ALZHEIMER'S DISEASE BY beta-AMYLOID PEPTIDES MASSACHUSETTS INST TECHNOLOGY (US) 2002-07-24 EP claimed
US-6172043-B1 GENETIC ENGINEERED POLYPEPTIDE MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2001-01-09 US claimed
EP-1015013-A1 TREATMENTS FOR NEUROTOXICITY IN ALZHEIMER'S DISEASE BY beta-AMYLOID PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2000-07-05 EP claimed
WO-1998030229-A1 TREATMENTS FOR NEUROTOXICITY IN ALZHEIMER'S DISEASE BY β-AMYLOID PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1998-07-16 WO claimed
CN-118084188-B Method for accelerating short-cut nitrification starting during sludge pretreatment SHANGHAI UNIVERSITY OF ELECTRIC POWER (CN) 2026-05-26 CN disclosed
WO-1998030229-A1 TREATMENTS FOR NEUROTOXICITY IN ALZHEIMER'S DISEASE BY β-AMYLOID PEPTIDES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 1998-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152694-A1 Methods and compositions for treating inflammatory disorders of the airways LTB4R2, LTB4R, LTC4S GRIA1 2085/4885GRIA3 2201/4885GRIA2 2341/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.