Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 20/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6525655 | 0.91 | BRAF (0.63) | BRAF | |
| SCHEMBL6525657 | 0.91 | BRAF (0.63) | BRAF | |
| SCHEMBL6522934 | 0.84 | BRAF (0.43) | BRAF | |
| SCHEMBL6522717 | 0.84 | BRAF (0.43) | BRAF | |
| SCHEMBL1074443 | 0.82 | BRAF (0.53) | BRAF | |
| SCHEMBL12830992 | 0.79 | BRAF (0.44) | BRAF | |
| SCHEMBL1494641 | 0.76 | BRAF (0.59) | BRAF | |
| SCHEMBL6522901 | 0.76 | BRAF (0.78) | BRAF | |
| SCHEMBL1494674 | 0.75 | BRAF (0.79) | BRAF | |
| SCHEMBL16105847 | 0.75 | BRAF (0.79) | BRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2470528-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | Novartis AG (CH) | 2012-07-04 | — | — | EP | disclosed |
| WO-2011023773-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2011-03-03 | — | — | WO | disclosed |