Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.47 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.46 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.43 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.43 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.43 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.43 |
| ▸ | PLA2G12B | Q9BX93 | 1/20 | 0.43 |
| ▸ | PLA2G12A | Q9BZM1 | 1/20 | 0.43 |
| ▸ | PLA2G2F | Q9BZM2 | 1/20 | 0.43 |
| ▸ | PLA2G3 | Q9NZ20 | 1/20 | 0.43 |
| ▸ | PLA2G2E | Q9NZK7 | 1/20 | 0.43 |
| ▸ | PLA2G2D | Q9UNK4 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20272596 | 1.00 | TDP1 (0.47) | TDP1PSMB8PSMB5FFAR1TBXAS1 | |
| SCHEMBL13604872 | 0.86 | ESR1 (0.53) | TDP1FFAR1TBXAS1PLA2G10PLA2G2A | |
| SCHEMBL12406009 | 0.86 | KDM6B (0.49) | TDP1FFAR1TBXAS1PLA2G10PLA2G2A | |
| SCHEMBL17739986 | 0.85 | PSMB5 (0.43) | TDP1PSMB8PSMB5SMN1; SMN2CTSB | |
| SCHEMBL12035913 | 0.84 | AKR1C3 (0.44) | FFAR1TBXAS1PLA2G10PLA2G2APLA2G1B | |
| SCHEMBL391961 | 0.84 | FFAR1 (0.47) | TDP1FFAR1TBXAS1POLBLMNA | |
| SCHEMBL14114904 | 0.82 | PSMB8 (0.45) | TDP1PSMB8PSMB5SMN1; SMN2CTSB | |
| SCHEMBL11237591 | 0.82 | TBXAS1 (0.59) | FFAR1TBXAS1LDHAPTGS1PTGS2 | |
| SCHEMBL31561604 | 0.82 | PSMB8 (0.48) | TDP1PSMB8PSMB5CTSBPOLB | |
| SCHEMBL12035920 | 0.80 | EPHX2 (0.49) | FFAR1TBXAS1PLA2G10PLA2G2APLA2G1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9150899-B2 | Identification of compounds modifying a cellular response | 2CUREX (DK) | 2015-10-06 | — | — | US | disclosed |
| US-20130123140-A1 | IDENTIFICATION OF COMPOUNDS MODIFYING A CELLULAR RESPONSE | 2CUREX (DK) | 2013-05-16 | — | — | US | disclosed |