Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12136711 | 0.89 | MAPT (0.58) | MAPTALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL12136709 | 0.83 | MAPT (0.65) | MAPTALDH1A1KDM4EHPGDALOX12 | |
| SCHEMBL18687248 | 0.73 | MAPT (0.76) | MAPTALDH1A1KDM4EHPGDLMNA | |
| SCHEMBL12136699 | 0.73 | MAPT (0.52) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL12136703 | 0.73 | MAPT (0.52) | MAPTALDH1A1KDM4ELMNARAB9A | |
| SCHEMBL14947262 | 0.72 | MAPT (0.51) | MAPTALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL14947263 | 0.72 | MAPT (0.51) | MAPTALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL12658341 | 0.71 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4EHTTMEN1 | |
| SCHEMBL12658257 | 0.71 | MAPT (0.49) | MAPTALDH1A1KDM4ERAB9AHTT | |
| SCHEMBL12658258 | 0.70 | MAPT (0.48) | MAPTALDH1A1KDM4ERAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9017701-B2 | Organogel compositions comprising alkylated benzimidazolones | XEROX CORPORATION (US) | 2015-04-28 | — | — | US | disclosed |
| US-20130123375-A1 | Organogel Compositions Comprising Alkylated Benzimidazolones | NATIONAL RESEARCH COUNCIL OF CANADA (CA) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123375-A1 | Organogel Compositions Comprising Alkylated Benzimidazolones | BLM, SBK3, CHEK2 | MAPT 1891/4885ALDH1A1 1114/4885KDM4E 2561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.