Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.63 |
| ▸ | MAOA | P21397 | 2/20 | 0.63 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | NR1H4 | Q96RI1 | 3/20 | 0.58 |
| ▸ | ABCG2 | Q9UNQ0 | 4/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 1/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.55 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947395 | 0.81 | ABCB1 (0.70) | MAOBCYP1A2CYP2D6ABCG2MEN1 | |
| SCHEMBL29443563 | 0.80 | MAPT (0.82) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3452239 | 0.79 | FOS (0.62) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3452240 | 0.79 | FOS (0.62) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL15932965 | 0.79 | MAOB (0.58) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29975428 | 0.79 | FOS (0.62) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25195536 | 0.79 | ABCG2 (0.73) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30383421 | 0.79 | ABCG2 (0.73) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30383999 | 0.78 | MAOB (0.65) | MAOBMAOACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL25191020 | 0.78 | MAOB (0.65) | MAOBMAOACYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MEDIZINISCHE UNIVERSITAT WIEN (AT) | 2013-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130123367-A1 | VINYLOGOUS CHALCONE DERIVATIVES AND THEIR MEDICAL USE | MALT1, VHL, ETV6 | MAOB 3578/4885MAOA 4115/4885CYP1A2 36/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.