SCHEMBL14947748

SCHEMBL14947748

CNCCCC[C@H](N)C(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KISS1R Q969F8 1/20 0.47
DPP7 Q9UHL4 2/20 0.43
GNAI3 P08754 1/20 0.41
GNAO1 P09471 1/20 0.41
GNAI1 P63096 1/20 0.41
NOS2 P35228 5/20 0.38
NOS1 P29475 4/20 0.38
NOS3 P29474 3/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
TSHR P16473 1/20 0.38
GSR P00390 1/20 0.38
BLM P54132 1/20 0.37
CPB2 Q96IY4 1/20 0.36
RRM1 P23921 1/20 0.36
MEN1 O00255 1/20 0.35
CYP2C19 P33261 1/20 0.35
KMT2A Q03164 1/20 0.35
SLC15A1 P46059 1/20 0.35
EPHX1 P07099 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12825453 1.00 KISS1R (0.47) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL1104625 1.00 KISS1R (0.47) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL13776588 0.94 KISS1R (0.53) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL16602285 0.94 KISS1R (0.53) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL15132881 0.94 KISS1R (0.53) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL24390551 0.89 DPP7 (0.60) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL18752843 0.89 DPP7 (0.60) KISS1RDPP7GNAI3GNAO1GNAI1
SCHEMBL10126254 0.85
SCHEMBL12513982 0.85
SCHEMBL22381010 0.84 GSR (0.48) DPP7NOS2NOS1NOS3CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240218164-A1 POLYMER COMPOSITION AND PREPARATION METHOD THEREFOR YOUREH CO., LTD. (KR) 2024-07-04 US disclosed
WO-2023152347-A1 PROCESS FOR MANUFACTURING MACROCYCLIC PEPTIDES F. HOFFMANN-LA ROCHE AG (CH) 2023-08-17 WO disclosed
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2023-05-11 US disclosed
WO-2023012263-A1 SOLID ORAL PEPTIDE FORMULATIONS NOVO NORDISK A/S (DK) 2023-02-09 WO disclosed
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2022-05-05 US disclosed
US-11174301-B2 Peptide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-11-16 US disclosed
WO-2021193983-A2 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-09-30 WO disclosed
WO-2021193984-A2 QD DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2021-09-30 WO disclosed
US-20200140505-A1 PEPTIDE COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMTED (JP) 2020-05-07 US disclosed
US-10435445-B2 Peptide compound TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2019-10-08 US disclosed
US-9890315-B2 Use of polylysine as a shale inhibitor BASF SE (DE) 2018-02-13 US disclosed
EP-2737000-B1 USE OF HYPERBRANCHED POLYLYSINE AS SHALE INHIBITOR BASF SE (DE) 2017-06-07 EP disclosed
WO-2016046409-A1 NOVEL PEPTIDE DERIVATIVES AND USES THEREOF NOSOPHARM (FR) 2016-03-31 WO disclosed
EP-2057188-B1 DPP-IV RESISTANT GIP HYBRID POLYPEPTIDES WITH SELECTABLE PROPERTIES AMYLIN PHARMACEUTICALS LLC (US) 2013-07-31 EP disclosed
WO-2013074526-A2 ANTIMICROBIAL COMPOSITIONS AND METHODS OF USE THEREOF BYOCOAT ENTERPRISES, INC. (US) 2013-05-23 WO disclosed
US-20130123148-A1 USE OF POLYLYSINE AS A SHALE INHIBITOR BASF SE (DE) 2013-05-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200140505-A1 PEPTIDE COMPOUND GIPR, GLP1R, GRPR KISS1R 111/4885DPP7 79/4885GNAI3 429/4885
US-20230143604-A1 QW DOSING OF GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, GRPR KISS1R 87/4885DPP7 90/4885GNAI3 203/4885
US-11174301-B2 Peptide compound GIPR, GLP1R, GRPR KISS1R 111/4885DPP7 79/4885GNAI3 429/4885
US-10435445-B2 Peptide compound GIPR, GLP1R, GRPR KISS1R 103/4885DPP7 71/4885GNAI3 388/4885
US-20220135638-A1 GIP RECEPTOR AGONIST PEPTIDE COMPOUNDS AND USES THEREOF GIPR, GLP1R, VIPR1 KISS1R 50/4885DPP7 115/4885GNAI3 330/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.