Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 12/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.39 |
| ▸ | CHKA | P35790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14950986 | 0.85 | APP (0.54) | APPCYP3A4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL12646538 | 0.83 | APP (0.68) | APPCYP3A4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL14948220 | 0.78 | APP (0.56) | APPCYP3A4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL595602 | 0.74 | APP (0.61) | APPALDH1A1KDM4EMAPTTSHR | |
| SCHEMBL14948221 | 0.74 | SLC2A1 (0.59) | APPCYP3A4ALDH1A1KDM4EMAPT | |
| SCHEMBL1309989 | 0.73 | GAA (0.66) | APPCYP3A4ALDH1A1KDM4EMAPT | |
| SCHEMBL270793 | 0.72 | SMN1; SMN2 (0.68) | APPCYP3A4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL9818198 | 0.72 | SMN1; SMN2 (0.68) | CYP3A4SMN1; SMN2ALDH1A1KDM4EMAPT | |
| SCHEMBL4254052 | 0.72 | SMN1; SMN2 (0.68) | CYP3A4SMN1; SMN2ALDH1A1KDM4ENR1I2 | |
| SCHEMBL79031 | 0.72 | SMN1; SMN2 (0.68) | CYP3A4SMN1; SMN2ALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210063411-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MED SYST INC (US) | 2021-03-04 | — | — | US | disclosed |
| US-10883999-B2 | Detecting targets using mass tags and mass spectrometry | VENTANA MEDICAL SYSTEMS, INC. (US) | 2021-01-05 | — | — | US | disclosed |
| US-20190004061-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MED SYST INC (US) | 2019-01-03 | — | — | US | disclosed |
| US-20160139143-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2016-05-19 | — | — | US | disclosed |
| US-9291597-B2 | Detecting targets using mass tags and mass spectrometry | VENTANA MEDICAL SYSTEMS, INC. (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130122516-A1 | DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY | VENTANA MEDICAL SYSTEMS, INC. | 2013-05-16 | — | — | US | disclosed |