SCHEMBL14948221

SCHEMBL14948221

CN(C)c1ccc(C(c2ccc(OCCO)cc2)c2ccc(N(C)C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.59
APP P05067 12/20 0.57
PTGES O14684 1/20 0.46
HDAC1 Q13547 1/20 0.46
NR1I2 O75469 1/20 0.45
ALDH1A1 P00352 2/20 0.44
RECQL P46063 1/20 0.44
MAPT P10636 2/20 0.43
TSHR P16473 2/20 0.43
KDM4E B2RXH2 1/20 0.43
RAB9A P51151 1/20 0.43
MCL1 Q07820 1/20 0.43
HSD17B10 Q99714 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPK1 P28482 1/20 0.42
PHLPP2 Q6ZVD8 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12646538 0.89 APP (0.68) APPPTGESHDAC1NR1I2ALDH1A1
SCHEMBL9818175 0.86 ALDH1A1 (0.58) APPNR1I2ALDH1A1RECQLRAB9A
SCHEMBL18102770 0.85 SLC2A1 (0.61) SLC2A1APPPTGESHDAC1ALDH1A1
SCHEMBL15432759 0.83 SLC2A1 (0.59) SLC2A1APPPTGESHDAC1MAPT
SCHEMBL825924 0.83 SLC2A1 (0.64) SLC2A1APPPTGESHDAC1ALDH1A1
SCHEMBL14198833 0.83 NR1I2 (0.45) SLC2A1APPNR1I2ALDH1A1RECQL
SCHEMBL10875478 0.81 SLC2A1 (0.65) SLC2A1APPPTGESALDH1A1MAPT
SCHEMBL9626190 0.81 SLC2A1 (0.65) SLC2A1APPPTGESALDH1A1MAPT
SCHEMBL5011707 0.81 SLC2A1 (0.56) SLC2A1PTGESHDAC1TSHR
SCHEMBL595602 0.80 APP (0.61) APPPTGESHDAC1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210063411-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MED SYST INC (US) 2021-03-04 US disclosed
US-10883999-B2 Detecting targets using mass tags and mass spectrometry VENTANA MEDICAL SYSTEMS, INC. (US) 2021-01-05 US disclosed
US-20190004061-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MED SYST INC (US) 2019-01-03 US disclosed
EP-2588144-B1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MED SYST INC (US) 2018-05-09 EP disclosed
US-20160139143-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MEDICAL SYSTEMS, INC. 2016-05-19 US disclosed
US-20160139143-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MEDICAL SYSTEMS, INC. 2016-05-19 US disclosed
US-9291597-B2 Detecting targets using mass tags and mass spectrometry VENTANA MEDICAL SYSTEMS, INC. (US) 2016-03-22 US disclosed
US-9291597-B2 Detecting targets using mass tags and mass spectrometry VENTANA MEDICAL SYSTEMS, INC. (US) 2016-03-22 US disclosed
US-20130122516-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MEDICAL SYSTEMS, INC. 2013-05-16 US disclosed
US-20130122516-A1 DETECTING TARGETS USING MASS TAGS AND MASS SPECTROMETRY VENTANA MEDICAL SYSTEMS, INC. 2013-05-16 US disclosed