SCHEMBL14948322

SCHEMBL14948322

Cc1ccc2cc(N(c3ccc4cc(C)ccc4c3)c3ccc4cc(C[N+](C)(C)C)ccc4c3)ccc2c1

nearest known ligand 0.42

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 4/20 0.42
CYP1A2 P05177 4/20 0.42
TDP1 Q9NUW8 2/20 0.37
SLC6A2 P23975 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35
HTT P42858 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
NCK1 P16333 1/20 0.32
BACE1 P56817 1/20 0.32
BMP1 P13497 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14948394 0.83 CYP2A6 (0.36) CYP2A6CYP1A2TDP1L3MBTL1KDM4E
SCHEMBL14948325 0.82 CYP2A6 (0.40) CYP2A6CYP1A2TDP1SLC6A2SLC6A4
SCHEMBL13304731 0.80 CYP1A2 (0.65) CYP2A6CYP1A2TDP1HTTNPSR1
SCHEMBL14948326 0.80 CYP2A6 (0.41) CYP2A6CYP1A2TDP1SLC6A2SLC6A4
SCHEMBL14948317 0.79 SLC6A2 (0.37) CYP2A6CYP1A2SLC6A2SLC6A4SLC6A3
SCHEMBL14948435 0.77 CYP2A6 (0.45) CYP2A6CYP1A2TDP1SLC6A2SLC6A4
SCHEMBL14948316 0.77 ALDH1A1 (0.45) CYP2A6CYP1A2TDP1KDM4EALDH1A1
SCHEMBL13868389 0.77 CYP1A2 (0.59) CYP2A6CYP1A2TDP1HTTNPSR1
SCHEMBL14948437 0.75 CYP2A6 (0.47) CYP2A6CYP1A2TDP1SLC6A2SLC6A4
SCHEMBL14948319 0.75 ALDH1A1 (0.41) TDP1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9184388-B2 Layered structure, electronic device using same, aromatic compound, and method for manufacturing said compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2015-11-10 US disclosed
US-20130119369-A1 LAYERED STRUCTURE, ELECTRONIC DEVICE USING SAME, AROMATIC COMPOUND, AND METHOD FOR MANUFACTURING SAID COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2013-05-16 US disclosed